Caspase-9 (Human) ELISA Kit

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.This kit was based on sandwich enzyme-linked immune-sorbent assay technology. The density of color is proportional to the Human Caspase-9 amount of sample captured in plate.

• Detection method: Absorbance (450 nm) • Species reactivity: Human • Application: quantitative measurement of Caspase:9 in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Easy, convenient and time-saving method to measure the level of Casepase-9 in serum, plasma, tissue homogenates, culture supernatants and other biological fluids. Detection Range: 1.563-100 ng/ml Sensitivity: < 0.938 ng/ml

ELISA kit

Caspase-9 (Human) ELISA Kit

• Microplate: 96 wells • Lyophilized Standard • Sample / Standard dilution buffer • Biotin- detection antibody (Concentrated) • Antibody dilution buffer • HRP-Streptavidin Conjugate (SABC) • SABC dilution buffer • TMB substrate • Stop Solution • Wash buffer (25X) • Plate sealers

4°C

gel pack

6 months

Human

Quantitative measurement of Caspase-9 in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED