QuickDetect™ CD163 (Human) ELISA Kit

Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. BioVision’s QuickDetect™ CD163 ELISA kit is a sandwich ELISA assay for measuring the quantity of human CD163 in serum, plasma and cell culture and other biological fluid. The entire process can be performed within 90 minutes with only a single incubation and a wash step respectively, resulting in fewer handling steps, fewer errors and more consistent results.

• Detection method: Absorbance (450 nm) • Species reactivity: Human • Application: quantitative measurement of CD163 in human serum, plasma, cell culture supernatant, and other biological fluid.

Easy, convenient and time-saving method to measure the level of CD163 in human serum, plasma, culture supernatants and other biological fluids. The entire assay can be performed within 90 minutes with only a single incubation and a wash step respectively, resulting in fewer handling steps, fewer errors and more consistent results. Detection Range: 9.3 - 300 ng/ml

ELISA kit

none

• Micro ELISA Plate • Standard • Standard Diluent • Special Diluent • HRP-Conjugate Reagent • Chromogen Solution A • Chromogen Solution B • Stop Solution • Wash buffer (20X) • Sealed bags • Microplate Sealers

4°C

gel pack

6 months

Human

Quantitative measurement of CD163 in human serum, plasma, cell culture supernatant and other biological fluids.

Human serum, plasma, tissue homogenates and other biological fluids.

E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED