QuickDetect™ Clusterin/Apo-J (Human) ELISA Kit

Clusterin functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation. Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement. Plays a role in the regulation of cell proliferation. BioVision’s QuickDetectTM Clusterin ELISA kit is a sandwich ELISA assay for measuring the quantity of human Clusterin in serum, plasma and cell culture and other biological fluid. The entire process can be performed within 90 minutes with only a single incubation and a wash step respectively, resulting in fewer handling steps, fewer errors and more consistent results.

• Detection method: Absorbance (450 nm) • Species reactivity: Human • Application: quantitative measurement of Clusterin in human serum, plasma, cell culture supernatant, and other biological fluid.

Easy, convenient and time-saving method to measure the level of Clusterin in human serum, plasma, culture supernatants and other biological fluids. The entire assay can be performed within 90 minutes with only a single incubation and a wash step respectively, resulting in fewer handling steps, fewer errors and more consistent results. Detection Range: 3.7 - 120 ng/ml

ELISA kit

none

• Micro ELISA Plate • Standard • Standard Diluent • Special Diluent • HRP-Conjugate Reagent • Chromogen Solution A • Chromogen Solution B • Stop Solution • Wash buffer (20X) • Microplate Sealers • Sealed bags

4°C

gel pack

6 months

Human

Quantitative measurement of Clusterin in human serum, plasma, cell culture supernatant and other biological fluids.

Human serum, plasma, cell culture supernatant, tissue homogenate and other biological fluids.

E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED