Human Monoclonal Anti-PRMT6 Antibody (2C3-F1-G1)

Human Monoclonal antibody to detect PRMT6

Human

Monoclonal Antibody (Clone#2C3-F1-G1)

Human

Recombinant human PRMT6 protein fragments expressed in E.coli

PRMT6 (HRMT1L6)

Epigenetics

55170

Q96LA8

Colorless liquid

Affinity purified antibody is supplied in liquid form in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Affinity purified

Western blot: HeLa and 293T cell lysate; Immunofluorescence: Hela cells; Immunohistochemistry: human breast cancer tissue

Western blot; 1:1000; Immunofluorescence; 1:300; Immunohistochemistry

PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.

Before use gently mix the antibody solution. Store this antibody at -20 °C for 12 months. Refer to the label on vial

Shipped to your lab under gel pack

Manifactured in USA. For Research Use Only! Not to be used in humans

This antibody is available to order since May 2017

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

anticorps