Mouse Monoclonal Anti-SMARCC1 Antibody (2A4-H7-C12)

Mouse Monoclonal antibody to detect SMARCC1

Mouse

Monoclonal Antibody (Clone#2A4-H7-C12)

Human

Recombinant human SMARCC1 protein fragments expressed in E.coli

SMARCC1 (BRG1-associated factor 155, BAF155, SWI/SNF complex 155 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1)

Epigenetics

6599

Q92922

Colorless liquid

Affinity purified antibody is supplied in liquid form in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol

Affinity purified

Western blot: K562, Jurkat and HeLa cell lysates

Western blot; 1:1000

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.

Before use gently mix the antibody solution. Store this antibody at -20 °C for 12 months. Refer to the label on vial

Shipped to your lab under gel pack

Manifactured in USA. For Research Use Only! Not to be used in humans

This antibody is available to order since May 2017

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Mus musculus

anticorps