Mouse Monoclonal Anti-DCTN1 Antibody (3D5-C6-D5)

Mouse Monoclonal antibody to detect DCTN1

Mouse

Monoclonal Antibody (Clone#3D5-C6-D5)

Human

Recombinant human DCTN1 protein fragments expressed in E.coli

Dynactin subunit 1 (Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued)

Signal Transduction

1639

Q14203

Colorless liquid

Affinity purified antibody is supplied in liquid form in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol

Affinity purified

Western blot: K562, MCF7, 293T and HeLa cell lysates, Immunoprecipitation: HeLa cells

Western blot; 1:500

Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule.

Before use gently mix the antibody solution. Store this antibody at -20 °C for 12 months. Refer to the label on vial

Shipped to your lab under gel pack

Manifactured in USA. For Research Use Only! Not to be used in humans

This antibody is available to order since May 2017

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Mus musculus

anticorps