Human D-Serine Dehydratase Active Recombinant protein

Catalog number
P1193-500
Name
Human D-Serine Dehydratase Active Recombinant protein
Size
500 μg
Price
751.00 EUR
Supplier
Biovision
Order

Details

Scientific context
D-Serine Dehydratase belongs to the β- family of the Pyridoxal phosphate-dependent enzymes and part of the fold-type II family. It binds to one catalytically essential PLP per protein molecule but also contains another low affinity PLP binding site. The enzyme converts D-Serine, D-threonine, D-allo-Threonine to corresponding α-keto acid and ammonia. It is suggested to act as a detoxifying enzyme for E.Coli strains.
Specific targetted sequence
N/A
Molecular weight (in Da)
47.8 kDa
Protein target
D-Serine Dehydratase
Other name
DsdSC, D-serine deaminase, DSD, DSD2
Gene origin
Saccharomyces cerevisiae
Gene number
852679 (DSD1)
Protein number
P53095
Source
E.coli
Application
SDS-PAGE (Purity > 95% )
Endotoxins
N/A
Specific activity
The specific activity (specifications/test method) was measured by its ability to metabolizes 1 μmole of D-serine into pyruvate per minute at 37°C and pH 7.4, in the presence of pyridoxal-5-phosphate and catalytic Zn2+.
Bioactivity
The specific bioactivity is ≥ 60 mU/mg
Example results
Expected results ≥ 60 mU/mg
Unit Definition
One Unit of DsdSC metabolizes 1 μmole of D-serine into pyruvate per minute at 37°C and pH 7.4, in the presence of pyridoxal-5-phosphate and catalytic Zn2+.
Handling and storage
Centrifuge the vial prior to opening. Store for 12 months at -20°C
Delivery
Shipped under gel pack
Package form
This product is supplied as lyophilized form from 50 mM Sodium phosphate, pH 7.0, 30% glycerol
Reconstitute
Reconstitute in 50 mM potassium phosphate, 50 mM NaCl, pH 7.4.
Precautions
Manufactured in USA. For Research Use Only! Not to be used in humans
Released
Manifactured since May 2017. Available to order. Please contact us for larger or bulk quantity
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants
Description
Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.