Human WNT-7a Recombinant protein

Catalog number
P1195-100
Name
Human WNT-7a Recombinant protein
Size
100 μg
Price
588.00 EUR
Supplier

Details

Scientific context
WNT7A is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. Recombinant human WNT7A protein, fused to His-tag at N-terminus, was expressed in E.coli.
Specific targetted sequence
MGSSHHHHHH SSGLVPRGSH MGSLGASIIC NKIPGLAPRQ RAICQSRPDA IIVIGEGSQM GLDECQFQFR NGRWNCSALG ERTVFGKELK VGSREAAFTY AIIAAGVAHA ITAACTQGNL SDCGCDKEKQ GQYHRDEGWK WGGCSADIRY GIGFAKVFVD AREIKQNART LMNLHNNEAG RKILEENMKL ECKCHGVSGS CTTKTCWTTL PQFRELGYVL KDKYNEAVHV EPVRASRNKR PTFLKIKKPL SYRKPMDTDL VYIEKSPNYC EEDPVTGSVG TQGRACNKTA PQASGCDLMC CGRGYNTHQY ARVWQCNCKF HWCCYVKCNT CSERTEMYTC K
Molecular weight (in Da)
38.0 kDa
Protein target
WNT7A
Other name
WNT7A, Protein Wnt-7a
Gene origin
Human
Gene number
7476 (WNT7A)
Protein number
O00755
Source
E.coli
Application
SDS-PAGE (Purity > 85%)
Endotoxins
N/A
Specific activity
N/A
Bioactivity
N/A
Example results
N/A
Unit Definition
N/A
Handling and storage
Centrifuge the vial prior to opening. Store for 12 months at -20°C
Delivery
Shipped under gel pack
Package form
This product is supplied as liquid form in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Reconstitute
See included datasheet or contact our technical support
Precautions
Manufactured in USA. For Research Use Only! Not to be used in humans
Released
Manifactured since May 2017. Available to order. Please contact us for larger or bulk quantity
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants