Human CellExp LILRB4 Recombinant protein

Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

N/A

28.0 kDa

LILRB4

LILRB4, ILT3, LIR5, CD85K, HM18

Cynomolgus

107128256 (LILRB4)

XP_015297198.1

HEK293 cells

SDS-PAGE (Purity > 90% )

N/A

N/A

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N/A

Centrifuge the vial prior to opening. Store for 12 months at -20°C

Shipped under gel pack

This product is supplied as lyophilized form from 0.22 μm filtered solution in PBS pH 7.4

Reconstitute in distilled water.

Manufactured in USA. For Research Use Only! Not to be used in humans

Manifactured since May 2017. Available to order. Please contact us for larger or bulk quantity

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Recombinants or rec. proteins

recombinants