Human CellExp LILRB4 / CD85k / ILT3 Recombinant protein
Catalog number
P1200-10
Name
Human CellExp LILRB4 / CD85k / ILT3 Recombinant protein
Size
10 μg
Price
186.00 EUR
Supplier
Details
Scientific context
Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Specific targetted sequence
N/A
Molecular weight (in Da)
26.0 kDa
Protein target
LILRB4
Other name
LILRB4, ILT3, LIR5, CD85K, HM18
Gene origin
Mouse
Gene number
14728 (LILRB4)
Protein number
Q64281
Source
HEK293 cells
Application
SDS-PAGE (Purity > 95% )
Endotoxins
< 1.0 EU per/μg
Specific activity
N/A
Bioactivity
N/A
Example results
N/A
Unit Definition
N/A
Handling and storage
Centrifuge the vial prior to opening. Store for 12 months at -20°C
Delivery
Shipped under gel pack
Package form
This product is supplied as lyophilized form from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitute
Reconstitute in sterile deionized water to the desired protein concentration.
Precautions
Manufactured in USA. For Research Use Only! Not to be used in humans
Released
Manifactured since May 2017. Available to order. Please contact us for larger or bulk quantity
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants
