Tie2 Kinase Inhibitor

4-(6-Methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole

Solid

N/A

948557-43-5

N/A

C26H21N3O2S

439.5

>98%

DMSO: 35 mg/mL (79.63 mM)

Protect from air and light

A potent and selective Tie2 inhibitor with IC50 of 0.25 Μm

-20°C

gel pack

36 months

MFCD18384977

23625762

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.