TGR5-Receptor-Agonist

TGR5-Receptor-Agonist; TGR5; 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide; MDK00245; MDK-00245; MDK 00245

Solid

N/A

1197300-24-5

N/A

C₁₈H₁₄Cl₂N₂O₂

361.22

>98%

DMSO

Protect from air and light

A potent TGR5 G-protein receptor (GPCR19) agonist

-20°C

gel pack

36 months

NA

44605616

Biochemicals

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.