Human CellExp CD27 Ligand/ CD70, Fc Tag, Mouse Recombinant

Catalog number
P1367-50
Name
Human CellExp CD27 Ligand/ CD70, Fc Tag, Mouse Recombinant
Size
50 µg
Price
545.00 EUR
Supplier

Details

Synonyms
CD70, CD27LG, TNFSF7, TNFSF7G, CD27L
Alternates names
CD70, CD27LG, TNFSF7, TNFSF7G, CD27L
Taglines
Cytokine that binds to CD27 and plays role in T-cell activation.
Biomolecule/Target
CD70
NCBI Gene ID #.
21948
NCBI Gene Symbol
CD70
Gene Source
Mouse
Accession #
O55237
Recombinant
Yes
Source
HEK 293 cells
Activity (Specifications/test method)
Measured by its binding ability in a functional ELISA
Biological activity
Immobilized Mouse CD27, Mouse IgG2a Fc Tag, at 2 μg/mL (100 μL/well) can bind Mouse CD27 Ligand (active trimer) with a linear range of 0.1-4 ng/mL
Results
N/A
Molecular Weight
18.6 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
12 months
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Reconstitution Instructions
Reconstitute in sterile deionized water to a concentration of 100 µg/ml.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used on humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name
Mus musculus
Additional source
Recombinants or rec. proteins
Group
recombinants