Caspase-Family Inhibitor Z-VAD-FMK

Z-VAD-FMK, Z-VAD fluoromethylketone, Caspase-Family Inhibitor, pan-caspase inhibitor

Liquid

In DMSO (10 mM)

187389-52-2

Z-Val-Ala-Asp(OMe)-FMK

C₂₂H₃₀N₃O₇F

467.5

Single spot by TLC

N/A

Protect from light and moisture

Caspase family Inhibitor

-20°C

gel pack

6-12 months

MFCD01074990

5737

Caspase Inhibitor

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.