Caspase-8 Inhibitor, Q-IETD-OPh

Q-IE(OMe)-TD(OMe)-OPh; Quinolyl-Ile-Glu(OMe)-Thr-Asp(OMe)-OPh

Off-white solid

N/A

N/A

N/A

C₃₈H₄₅F₂N₅O₁₁

785.78

N/A

DMSO

Protect from air and moisture

A caspase-8 inhibitor

-20°C

gel pack

24 months

N/A

44135280

Caspase Inhibitor

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.