Human CellExp FLT-3 Ligand, Human Recombinant
Catalog number
6452-50
Name
Human CellExp FLT-3 Ligand, Human Recombinant
Size
50 μg
Price
1165.00 EUR
Supplier
Details
Synonyms
Human Cellexp Human Recombinant FLT-3 Ligand
Alternates names
Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3.
Taglines
A member of a small family of growth factors that stimulate the proliferation of hematopoietic cells
Biomolecule/Target
NA
NCBI Gene ID #.
2322
NCBI Gene Symbol
FLT3
Gene Source
Human
Accession #
P36888
Recombinant
Yes
Source
Human 293 cell expressed
Purity
N/A
Endotoxin Level
< 1.0 EU per 1 μg of protein
Activity (Specifications/test method)
N/A
Biological activity
ED₅₀ is typically 0.2 to 0.8 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of the human acute myeloid leukemia cell line OCI-AML5.
Results
0.2 to 0.8 ng/ml
Molecular Weight
24 to 30 kDa, monomer, glycosylated
Storage Temp.
-20°C
Shipping
gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized from a PBS solution.
Reconstitution Instructions
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
Additional source
Recombinants or rec. proteins
Group
recombinants
