C646, p300/CBP Inhibitor

(E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid

Red solid

N/A

328968-36-1

N/A

C₂₄H₁₉N₃O₆

445.42

≥98% by NMR

DMSO (25 mM)

Protect from light and air

A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor

-20°C

gel pack

36 months

MFCD01784780

1285941

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.