Sphingosine Kinase Inhibitor, SKI-I

5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide

Pale yellow solid

N/A

306301-68-8

N/A

C₂₅H₁₈N₄O₂

406.44

≥90% by NMR

DMSO

Protect from air and light

A non-lipid sphingosine kinase (SK) inhibitor

-20°C

gel pack

24 months

N/A

N/A

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.