Sphingosine Kinase Inhibitor, SKI-II

4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

Off-white solid

N/A

312636-16-1

N/A

C₁₅H₁₁ClN₂OS

302.78

≥90% by NMR

DMSO (100 mM)

Protect from air and light

A non-lipid pan-sphingosine kinase (SK) inhibitor

-20°C

gel pack

24 months

MFCD00733553

753704

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.