Bromodomain Inhibitor, (+)-JQ1

t-Butyl-2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

Off-white solid

N/A

1268524-70-4

N/A

C₂₃H₂₅ClN₄O₂S

456.99

≥98% by HPLC

DMSO (10 mM)

Protect from air and moisture

A potent and highly specific BET inhibitor

-20°C

gel pack

24 months

MFCD19443648

46907787

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.