Human CellExp PD-1 /PDCD1, C-Fc Tag, mouse recombinant

Catalog number
7503-50
Name
Human CellExp PD-1 /PDCD1, C-Fc Tag, mouse recombinant
Size
50 μg
Price
845.00 EUR
Supplier

Details

Synonyms
PD, PD 1, PD 1 protein, PD 1 recombinant protein, mouse PD 1 protein, mouse recombinant PD 1 protein, mouse recombinant PD 1, mouse PD 1, recombinant PD 1, Human cell expressed PD 1, Human cell expressed PD 1 protein, Human cell expressed recombinant PD 1, Human cell expressed recombinant PD 1 protein, PD, PD-1, PD-1 protein, PD-1 recombinant protein, mouse PD-1 protein, mouse recombinant PD-1 protein, mouse recombinant PD-1, mouse PD-1, recombinant PD-1, Human cell expressed PD-1, Human cell expressed PD-1 protein, Human cell expressed recombinant PD-1, Human cell expressed recombinant PD-1 protein, PD, PD1, PD1 protein, PD1 recombinant protein, mouse PD1 protein, mouse recombinant PD1 protein, mouse recombinant PD1, mouse PD1, recombinant PD1, Human cell expressed PD1, Human cell expressed PD1 protein, Human cell expressed recombinant PD1, Human cell expressed recombinant PD1 protein, PD1, PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l, October-RP-14, PDCD, PDCD 1, PDCD 1 protein, PDCD 1 recombinant protein, mouse PDCD 1 protein, mouse recombinant PDCD 1 protein, mouse recombinant PDCD 1, mouse PDCD 1, recombinant PDCD 1, Human cell expressed PDCD 1, Human cell expressed PDCD 1 protein, Human cell expressed recombinant PDCD 1, Human cell expressed recombinant PDCD 1 protein, PDCD, PDCD-1, PDCD-1 protein, PDCD-1 recombinant protein, mouse PDCD-1 protein, mouse recombinant PDCD-1 protein, mouse recombinant PDCD-1, mouse PDCD-1, recombinant PDCD-1, Human cell expressed PDCD-1, Human cell expressed PDCD-1 protein, Human cell expressed recombinant PDCD-1, Human cell expressed recombinant PDCD-1 protein, PDCD, PDCD1, PDCD1 protein, PDCD1 recombinant protein, mouse PDCD1 protein, mouse recombinant PDCD1 protein, mouse recombinant PDCD1, mouse PDCD1, recombinant PDCD1, Human cell expressed PDCD1, Human cell expressed PDCD1 protein, Human cell expressed recombinant PDCD1, Human cell expressed recombinant PDCD1 protein, PDCD1
Alternates names
PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l
Taglines
Inhibits the T-cell proliferation and production of IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway.
Biomolecule/Target
PD-1/PDCD1
NCBI Gene ID #.
18566
NCBI Gene Symbol
PDCD1
Gene Source
Mouse
Accession #
Q02242
Recombinant
Yes
Source
HEK293 cells
Purity
N/A
Activity (Specifications/test method)
N/A
Biological activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse PD-1 /PDCD1 Fc Chimera at 2 µg/mL (100 µl/well) can bind biotinylated Mouse PD-L1 with a linear range of 32 - 500 ng/mL.
Results
Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse PD-1 /PDCD1 Fc Chimera at 2 µg/mL (100 µl/well) can bind biotinylated Mouse PD-L1 with a linear range of 32 - 500 ng/mL.
Molecular Weight
This protein is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 43.2 kDa. The predicted N-terminus is Ser 21. DTT-reduced Protein migrates as 60-66 kDa in SDS-PAGE due to glycosylation.
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM glycine, pH 7.5. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name
Mus musculus
Additional source
Recombinants or rec. proteins
Group
recombinants