mTOR Inhibitor, WYE-23

4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester

White solid

N/A

1062169-46-3

N/A

C₂₆H₃₂N₈O₄

520.58

≥98% by HPLC

DMSO (>10 mg/ml)

Protect from light and moisture

A sub-nanomolar potent mTOR inhibitor

-20°C

gel pack

24 months

N/A

44233391

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.