Human CellExp PD-1 /PDCD1, human recombinant

Catalog number

7498-250

Size

250 μg

Price

1995.00 EUR

Supplier

Biovision

Order

Details

Synonyms

PD, PD 1, PD 1 protein, PD 1 recombinant protein, human PD 1 protein, human recombinant PD 1 protein, human recombinant PD 1, human PD 1, recombinant PD 1, Human cell expressed PD 1, Human cell expressed PD 1 protein, Human cell expressed recombinant PD 1

Alternates names

PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l

Taglines

Inhibits the T-cell proliferation and production of IL-1, IL-4, IL-10 and IFN-? by suppressing the activation and transduction of PI3K/AKT pathway.

Biomolecule/Target

PD-1/PDCD1

NCBI Gene ID #.

5133

NCBI Gene Symbol

PDCD1

Gene Source

Human

Accession #

Q15116

Recombinant

Yes

Source

HEK293 cells

Purity

N/A

Endotoxin Level

N/A

Activity (Specifications/test method)

Measured by its binding ability in a functional ELISA

Biological activity

Immobilized Human PD-1, His Tag at 5?g/mL (100 ?L/well) can bind Human PD-L1, His Tag with a linear range of 0.15-1.25 ?g/mL

Results

N/A

Molecular Weight

This protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 17.2 kDa. The predicted N-terminus is Leu 25. DTT-reduced Protein migrates as 25-40 kDa in SDS-PAGE due to glycosylation.

Storage Temp.

-20°C

Shipping

Gel Pack

Shelf Life

1 year

Concentration

N/A

Appearance

Lyophilized

Physical form description

Lyophilized from 0.22 ?m filtered solution in PBS pH 7.7

Reconstitution Instructions

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants