Human CellExp PD-1 /PDCD1, human recombinant

Catalog number
7498-1000
Name
Human CellExp PD-1 /PDCD1, human recombinant
Size
1 mg
Price
0.00 EUR
Supplier

Details

Synonyms
PD, PD 1, PD 1 protein, PD 1 recombinant protein, human PD 1 protein, human recombinant PD 1 protein, human recombinant PD 1, human PD 1, recombinant PD 1, Human cell expressed PD 1, Human cell expressed PD 1 protein, Human cell expressed recombinant PD 1
Alternates names
PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l
Taglines
Inhibits the T-cell proliferation and production of IL-1, IL-4, IL-10 and IFN-? by suppressing the activation and transduction of PI3K/AKT pathway.
Biomolecule/Target
PD-1/PDCD1
NCBI Gene ID #.
5133
NCBI Gene Symbol
PDCD1
Gene Source
Human
Accession #
Q15116
Recombinant
Yes
Source
HEK293 cells
Purity
N/A
Endotoxin Level
N/A
Activity (Specifications/test method)
Measured by its binding ability in a functional ELISA
Biological activity
Immobilized Human PD-1, His Tag at 5?g/mL (100 ?L/well) can bind Human PD-L1, His Tag with a linear range of 0.15-1.25 ?g/mL
Results
N/A
Molecular Weight
This protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 17.2 kDa. The predicted N-terminus is Leu 25. DTT-reduced Protein migrates as 25-40 kDa in SDS-PAGE due to glycosylation.
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized from 0.22 ?m filtered solution in PBS pH 7.8
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants