Human CellExp GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant

Catalog number
P1126-50
Name
Human CellExp GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant
Size
50 μg
Price
605.00 EUR
Supplier

Details

Synonyms
TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Alternates names
TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Taglines
Tumor necrosis factor receptor superfamily member 18
Biomolecule/Target
Tnfsf18
NCBI Gene ID #.
240873
NCBI Gene Symbol
Tnfsf18
Gene Source
Mouse
Accession #
Q7TS55
Recombinant
Yes
Source
HEK 293 cells
Purity
N/A
Endotoxin Level
< 1.0 EU per/μg
Activity (Specifications/test method)
Measured by its binding ability in a functional ELISA.
Biological activity
Immobilized Mouse GITR, His Tag at 10μg/mL (100 μL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 μg/mL.
Results
N/A
Molecular Weight
41.4 kDa
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Reconstitution Instructions
Reconstitute in sterile deionized water to the desired protein concentration.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name
Mus musculus
Additional source
Recombinants or rec. proteins
Group
recombinants