BCl-2 Inhibitor, ABT-199

Catalog number
2253-1
Name
BCl-2 Inhibitor, ABT-199
Size
2X1 mg
Price
310.00 EUR
Supplier

Details

Alternate Name/Synonyms
2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4’-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1’-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide; GDC-0199; Venetoclax
Appearance
White to off-white solid
Formulation
N/A
CAS Number
1257044-40-8
Peptide sequence
N/A
Molecular Formula
C₄₅H₅₀ClN₇O₇S
Molecular Weight
868.44
Purity
≥98% by HPLC
Solubility/Reconstitution Instructions
DMSO (50 mM)
Handling
Protect from light and moisture
Tagline
A potent BCl-2 inhibitor
Storage Temp.
-20°C
Shipping Conditions
gel pack
Shelf Life
24 months
MDL Number
N/A
PubChem CID
N/A
Category
Biochemicals
Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.