DUB Inhibitor, PR-619

2,6-Diaminopyridine-3,5-bis(thiocyanate), 3,5-Dithiocyanatopyridine-2,6-diamine

Yellow solid

N/A

2645-32-1

No

C₇H₅N₅S₂

223.28

≥98% by HPLC

DMSO (~ 5 mg/ml)

Protect from air and light

A deubiquitinylating enzymes (DUB) inhibitor

-20 ̊C

gel pack

36 months

MFCD00830384

N/A

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.