DNA methylation inhibitor, Dichlone

2,3-Dichloro-1,4-naphthoquinone, Dichlon

Yellow solid

N/A

117-80-6

N/A

C₁₀H₄Cl₂O₂

227.04

≥95% by GC

DMSO or EtOH

Protect from air and light

A DNA methylation inhibitor

-20°C

gel pack

36 months

MFCD00001677

8342

Biochemicals

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Non-methylated DNA at CpG islands organizes histone methylation through ZF-CxxC proteins in epigenetic biological systems. DNA and histone Methylation is catalyzed by enzymes; such methylation can be involved in hodyonr modification, regulation of gene expression, regulation of protein function, and RNA processing. Methylation of heavy metals can also occur outside biological systems. Chemical methylation of tissue samples is also one method for reducing certain histological staining artifacts. The counterpart of methylation is demethylation.