HLCL-61 hydrochloride for cell activation

Catalog number
B1209-25
Name
HLCL-61 hydrochloride for cell activation
Size
25 mg
Price
545.00 EUR
Supplier

Details

Description
HLCL-61 is a potent and selective PRMT5 (potent arginine methyltransferase 5) inhibitor. It shows no inhibitory activity against the type I (PRMT1 and PRMT4) and type II (PRMT7) PRMT family members. In vitro data shows HLCL-61 effectively inhibits symmetric arginine demethylation of histones H3 and H4 in AML samples. HLCL-61 treatment of cells showed decrease in cell vitality and effective in apoptosis promotion in MV-11 and THP-1 cells after 48 hours.
Peptide sequence
N/A
CAS number
586395-74-6 (free base).
Molecular weight
380.92
Category
Biochemicals
Other name
1-(9-ethyl-9H-carbazol-3-yl)-N-(2-methoxybenzyl)methanamine hydrochloride
Molecular formula
C₂₃H₂₅ClN₂O
Physical appearance
Crystalline Solid
Supplied with
N/A
Is this a salt?
Yes
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO(>20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.