Target of this antibody:
Alternative names of antibody target:
KCNIP3 , CSEN , DREAM , KCHIP3 , Calsenilin , KCHIP3 , MGC18289 , KChIP3
Calsenilin is also known as DREAM and KChlP3. Calsenilin interacts with presenilin-2, a protein involved in Alzheimer’s disease, to reverse presenilin mediated enhancement of calcium signaling. Calsenilin also has pro-apoptotic function, is a substrate for caspase-3, acts as a calcium regulated transcriptional suppressor, and interacts with A-type potassium channels.
Clonality of antibody:
This antibody reacts with:
Human, mouse, rat
Synthetic peptide surrounding amino acid 107 of human Calsenilin
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.2 mg/ml) Protein A affinity purified rabbit anti-Calsenilin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.1% BSA, 0.01% thimerosal.
This antibody has been succesfully tested for use in following methods:
Western blotting (2-6 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~30 kDa Calsenilin in samples from human, mouse, and rat origins. Jurkat cell lysate can be used as a positive control.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.