GANT58 for cell activation
Catalog number
1812-5
Name
GANT58 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC₅₀ ~ 5 µM in SAG-stimulated Shh-L2 cells) and displays anti-proliferative and antitumor activity in vivo.
Peptide sequence
N/A
CAS number
64048-12-0
Molecular weight
392.48
Category
Biochemicals
Other name
2,3,4,5-Tetra(4-pyridyl)thiophene; NSC75503
Molecular formula
C₂₄H₁₆N₄S
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (25 mM) or Ethanol (25 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
