Chidamide for cell activation

Catalog number
2261-1
Name
Chidamide for cell activation
Size
1 mg
Price
142.00 EUR
Supplier

Details

Description
Cell-permeable. A new benzamide class of histone deacetylase (HDAC) inhibitor with marked anti-tumor activity. It increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at concentrations as low as 4 µM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells.
Peptide sequence
No
CAS number
743420-02-2
Molecular weight
390.41
Category
Biochemicals
Other name
N-​(2-​amino-​5-​fluorophenyl)-​4-​[[[1-​oxo-​3-​(3-​pyridinyl)-​2-​propen-​1-​yl]amino]methyl]-​benzamide
Molecular formula
C₂₂H₁₉FN₄O₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from light and mositure
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.