Daminozide for cell activation

Catalog number
2438-100
Name
Daminozide for cell activation
Size
100 mg
Price
121.00 EUR
Supplier

Details

Description
A highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC₅₀ values of 1.5, 0.55, and 2.1 μM, respectively. When tested for inhibition of other demethylase subfamily members (KDM3, KDM4, KDM5, KDM6) and other 2OG oxygenases (FIH, PHD2, BBOX1), daminozide was considerably less potent (IC₅₀’s > 100 μM).
Peptide sequence
N/A
CAS number
1596-84-5
Molecular weight
160.17
Category
Biochemicals
Other name
1-​(2,​2-​dimethylhydrazide)-​butanedioic acid; Succinic acid mono(2,2-dimethylhydrazide)
Molecular formula
C₆H₁₂N₂O₃
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95%
Reconstitute instructions
DMSO (~15 mg/ml) or EtOH (~ 3 mg/ml) or H₂O (~ 15 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.