Compound 401 for cell activation

Catalog number
1657-5
Name
Compound 401 for cell activation
Size
5 mg
Price
238.00 EUR
Supplier

Details

Description
Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC₅₀ = 0.28 µM) that also targets mTOR (IC₅₀ = 5. 3µM), but not PI 3-K in vitro. Induces apoptosis in vitro.
Peptide sequence
N/A
CAS number
168425-64-7
Molecular weight
281.31
Category
Biochemicals
Other name
2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one
Molecular formula
C₁₆H₁₅N₃O₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥97% by HPLC
Reconstitute instructions
DMSO (10 mM) or EtOH (5 mM)
Storage condition
+4°C
Shipping condition
RT
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.