Thiostrepton for cell activation
Catalog number
9677-50
Name
Thiostrepton for cell activation
Size
50 mg
Price
121.00 EUR
Supplier
Details
Description
Thiostrepton is a large cyclic antibiotic commonly used in topical antibiotic ointments. It inhibits bacterial protein synthesis. It blocks translation by interfering with elongation factors (EF) involved in ribosomal GTPase activity. Antitumor agent; induces cell cycle arrest and apoptosis in breast cancer cells via downregulation of FOXM1 expression.
Peptide sequence
N/A
CAS number
1393-48-2
Molecular weight
1664.89
Category
Biochemicals
Other name
Alaninamide, Bryamycin, Thiactin
Molecular formula
C₇₂H₈₅N₁₉O₁₈S₅
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
Assay: ≥900 u/mg
Reconstitute instructions
DMSO (~5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
