Epoxomicin for cell activation

Catalog number
2190-50
Name
Epoxomicin for cell activation
Size
50 µg
Price
153.00 EUR
Supplier

Details

Description
Originally isolated from Actinomycetes strain based on its potent in vivo antitumor activity, Epoxomicin is a potent, cell-permeable, selective and irreversible proteasome inhibitor. More potent inhibitor of the chymotrypsin-like activity of the proteasome than Lactacystin (Cat. No. 1709-100). Blocks also trypsin-like and PGPH activities of the proteasome.
Peptide sequence
N/A
CAS number
134381-21-8
Molecular weight
554.7
Category
Biochemicals
Other name
N-​acetyl-​N-​methyl-​L-​isoleucyl-​L-​isoleucyl-​N-​[(1S)-​3-​methyl-​ 1-​[[(2R)-​2-​methyloxiranyl]carbonyl]butyl]-​L-​threoninamide; BU-4061T
Molecular formula
C₂₈H₅₀N₄O₇
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO (~ 10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.