Birinapant for cell activation

Catalog number

2597-1

Size

1 mg

Price

132.00 EUR

Supplier

Biovision

Order

Details

Description

Birinapant is a SMAC (synthetic small molecule and peptidomimetic of second mitochondrial-derived activator of caspases) mimetic and IAP (Inhibitor of Apoptosis Protein) antagonist with potential antineoplastic activity. Birinapant binds to and inhibits the activity of IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2. Since IAPs shield cancer cells from the apoptosis process, this agent may restore and promote the induction of apoptosis through apoptotic signaling pathways in cancer cells.

Peptide sequence

N/A

CAS number

1260251-31-7

Molecular weight

806.94

Category

Biochemicals

Other name

(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methyl]-1H-indol-2-yl]-1H-indol-3-yl]methyl]-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl]-2-(methylamino)propanamide; TL32711; SMAC mimetic

Molecular formula

C₄₂H₅₆F₂N₈O₆

Physical appearance

White to off-white solid

Supplied with

N/A

Is this a salt?

Is it cell-permeable?

Yes

Purification

>98% by HPLC

Reconstitute instructions