DBZ for cell activation
Catalog number
2649-1
Name
DBZ for cell activation
Size
1 mg
Price
132.00 EUR
Supplier
Details
Description
DBZ is a potent γ-secretase inhibitor that blocks the cleavage of Notch into its active signaling effector, Notch intracellular domain, in human T cell lymphoma (SupT1) cells (IC₅₀ = 1.7 nM).
Peptide sequence
N/A
CAS number
209984-56-5
Molecular weight
463.48
Category
Biochemicals
Other name
N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-benzeneacetamide
Molecular formula
C₂₆H₂₃F₂N₃O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 35 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
