Target of this antibody:
Alternative names of antibody target:
Sirtuin 7 (Silent mating type information regulation 2, homolog) 7 (S. cerevisiae) (Sirtuin 7 (Silent mating type information regulation 2, homolog) 7 (S. cerevisiae) (Predicted), isoform CRA_b)
SIRT7 is a member of the sirtuin family of proteins (Sir2-like proteins). All Sir2-like proteins are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins are not fully understood yet. Recent studies sμggested that bacterial, yeast and mammalian sirtuins are able to metabolize NAD and may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Clonality of antibody:
This antibody reacts with:
Human, mouse, rat
Synthetic peptide surrounding amino acid 400 of rat SIRT7
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti- SIRT7 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
This antibody has been succesfully tested for use in following methods:
Western Blot analysis (2-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3099BP-50) is available separately.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.