Target of this antibody:
Alternative names of antibody target:
PION, Gamma-secretase-activating protein, Protein pigeon homolog
GSAP, gamma-secretase activating protein interacts with gamma secretase which chops up the amyloid precursor protein to senile plaques in Alzheimer’s disease. GSAP was found to increase the production amyloid peptide. Immunohistochemistry to identify GSAP in brain can demonstrate its abundance in certain regions of damage, and is usually morphologically changed throughout the progression of Alzheimer's disease. GSAP can be used as a qualitative biomarker of Alzheimer's disease progression, and is regularly considered one of the best targets of therapies to diminish the effects of Alzheimer's disease in affected individuals.
Clonality of antibody:
This antibody reacts with:
Human, mouse, rat
Synthetic peptide close to C-terminal of GSAP
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) polyclonal antibody in PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.
Affinity Purified Antibody
This antibody has been succesfully tested for use in following methods:
Western Blot analysis (1-4 µg/ml).
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.