IGF-I, murine recombinant
Catalog number
4120-50
Name
IGF-I, murine recombinant
Size
50 μg
Price
335.00 EUR
Supplier
Details
Synonyms
Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Alternates names
Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Taglines
An endocrine hormone binding to IGF1R
Biomolecule/Target
IGF-I
NCBI Gene ID #.
16000
NCBI Gene Symbol
IGF1A
Gene Source
Mouse
Accession #
P05017
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
The ED₅₀ as determined by cell proliferation assay using FDC-P1 cells is 5 x 10⁵ units/mg. For most in vitro applications, the IGF-I exerts its biological activity in the concentration range of 1 to 20 ng/ml.
Molecular Weight
7.6 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Sterile filtered and lyophilized with no additives
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Description
IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
Additional source
Recombinants or rec. proteins
Group
recombinants
