IL-1 beta, rat recombinant

Catalog number
4130-50
Name
IL-1 beta, rat recombinant
Size
50 μg
Price
865.00 EUR
Supplier

Details

Synonyms
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Alternates names
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Taglines
An important mediator of inflammatory responses
Biomolecule/Target
IL-1 beta
NCBI Gene ID #.
UniGene:Rn.9869
NCBI Gene Symbol
IL1B
Gene Source
Rat
Accession #
Q63264
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is 1 x 10⁷ units/mg.
Molecular Weight
17.3 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Sterile filtered and then lyophilized from 10 mM Sodium Acetate, pH 6.5
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name
Rattus norvegicus
Additional source
Recombinants or rec. proteins
Group
recombinants