Y-27632, dihydrochloride for cell activation

Catalog number
1596-50
Name
Y-27632, dihydrochloride for cell activation
Size
50 mg
Price
2443.00 EUR
Supplier

Details

Description
Selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and>250 µM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase, respectively. Prevents apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem cells (hES) without affecting their pluripotency.
Peptide sequence
N/A
CAS number
146986-50-7
Molecular weight
320.26
Category
Biochemicals
Other name
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar boxamide dihydrochloride
Molecular formula
C₁₄H₂₁N₃O.2HCl
Physical appearance
White soild
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
H₂O (100 mM) or PBS (100 mM)
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.