Human CellExp™ TPO, Human Recombinant

Catalog number
6483-10
Name
Human CellExp™ TPO, Human Recombinant
Size
10 µg
Price
365.00 EUR
Supplier

Details

Background
TPO (Thrombopoietin, also known as Mpl-ligand, MGDF), a glycoprotein hormone produced mainly by the liver and the kidney, stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets.
Concentration
N/A
Molecular weight
80 to 85 kDa, monomer, glycosylated
Synonym
Human Cellexp Human Recombinant TPO
Other name
Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.
NCBI gene number
7066
NCBI gene
THPO
Gene source
Human
NCBI number
P40225
Recombinant
Yes
Source
Human 293 cell expressed
Purification
> 95%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
<1.0 EU per 1 μg of protein
Tested activity
N/A
Biological activity
ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of human M07e cells
Reesults
0.5 to 5 ng/ml
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized in PBS.
How to reconstitute
Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants