Gö 6976 for cell activation

Catalog number
1711-500
Name
Gö 6976 for cell activation
Size
500 µg
Price
208.00 EUR
Supplier

Details

Description
Cell-permeable. A potent protein kinase C (PKC) inhibitor (IC₅₀ = 7.9 nM). In vitro, discriminates between Ca²⁺-dependent and -independent isoforms of PKC; selectively inhibits PKCα and PKCβ1 (IC₅₀ values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKCδ, -ε, or -ζ (IC₅₀> 3µM).
Peptide sequence
N/A
CAS number
136194-77-9
Molecular weight
378.43
Category
Biochemicals
Other name
5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]py- rrolo[3,4-c]carbazole-12-propanenitrile; Go6976; PD 406976
Molecular formula
C₂₄H₁₈N₄O
Physical appearance
Off-white to yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.