Human CellExp™ CD48 / BCM1 / SLAMF2, human recombinant

Catalog number
7380-10
Name
Human CellExp™ CD48 / BCM1 / SLAMF2, human recombinant
Size
10 μg
Price
246.00 EUR
Supplier

Details

Target
CD48/BCM1/SLAMF2
Background
CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
Concentration
N/A
Molecular weight
This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 23.2 kDa. The predicted N-terminus is Gln 27. DTT-reduced Protein migrates as 38-45 kDa due to glycosylation.
Synonym
CD48, BCM1, SLAMF2, BLAST1, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
Other name
CD48, BCM1, SLAMF2, BLAST1, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
NCBI gene number
962
NCBI gene
CD48
Gene source
Human
NCBI number
P09326
Recombinant
Yes
Source
HEK293 cells
Purification
≥95%
Tested applications
SDS-PAGE, N/A
Tested activity
N/A
Biological activity
Measured by its binding ability in a functional ELISA. Immobilized human CD244 protein Fc Chimera at 5 μg/ml (100 μl/well) can bind human CD48 with a linear range of 0.1 - 4 μg/ml.
Reesults
Measured by its binding ability in a functional ELISA. Immobilized human CD244 protein Fc Chimera at 5 μg/ml (100 μl/well) can bind human CD48 with a linear range of 0.1 - 4 μg/ml.
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel Pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
How to reconstitute
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants