Renin Inhibitor for cell activation

Catalog number
2084-5
Name
Renin Inhibitor for cell activation
Size
5 mg
Price
262.00 EUR
Supplier

Details

Description
A non-peptide, direct renin inhibitor (IC50 = 0.6 nM for human renin) and an anti-hypertensive agent. Aliskiren confers neuronal resistance to Aβ toxicity in primary rat cortical cultures.
Peptide sequence
N/A
CAS number
173334-58-2
Molecular weight
609.79
Category
Biochemicals
Other name
Aliskiren Hemifumarate; (2S,4S,5S,7S)-N-(2-Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide hemifumarate
Molecular formula
C₃₀H₅₃N₃O₆ • ½C₄H₄O₄
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (>100 mg/ml) or H2O (>100 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.