PLX-4032 for cell activation

Catalog number
2235-25
Name
PLX-4032 for cell activation
Size
25 mg
Price
327.00 EUR
Supplier

Details

Description
Cell-permeable. A potent, selective and ATP-competitive, inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. PLX-40432 selectively binds to the ATP-binding site of BRAF(V600E) kinase and inhibits its activity, which may result in an inhibition of an over-activated MAPK signaling pathway downstream in BRAF(V600E) kinase-expressing tumor cells and a reduction in tumor cell proliferation.
Peptide sequence
N/A
CAS number
1029872-54-5
Molecular weight
489.92
Category
Biochemicals
Other name
Vemurafenib; RG7204, RO5185426
Molecular formula
C₂₃H₁₈ClF₂N₃O₃S
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥99%
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.