GSK-J1 sodium salt for cell activation

Catalog number
2260-1
Name
GSK-J1 sodium salt for cell activation
Size
1 mg
Price
115.00 EUR
Supplier

Details

Description
A potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX (IC₅₀ = 60 nM for human JMJD3 in vitro). It is inactive against a panel of other JMJ family demethylases, including several variants of JMJD2 and JMJD1 and, at higher concentrations (30 μM), has no effect on more than 100 different kinases or other unrelated proteins, including other chromatin-modifying enzymes such as histone deacetylases.
Peptide sequence
No
CAS number
N/A
Molecular weight
411.43
Category
Biochemicals
Other name
3-​((6-​(4,​5-​dihydro-​1H-​benzo[d]azepin-​3(2H)-​yl)-​2-​(pyridin-​2-​yl)pyrimidin-4-yl)amino)propanoate, monosodium salt
Molecular formula
C₂₂H₂₂N₅O₂ ∙ Na
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥95%
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from light and mositure
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.