Human CellExp™ CD45, human recombinant

Catalog number
P1015-10
Name
Human CellExp™ CD45, human recombinant
Size
10 µg
Price
251.00 EUR
Supplier

Details

Target
PTPRC
Background
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexs or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.
Concentration
N/A
Molecular weight
65kDa
Synonym
LCA; LY5; B220; T200; CD45R; GP180; PTPRC
Other name
LCA; LY5; B220; T200; CD45R; GP180; PTPRC
NCBI gene number
5788
NCBI gene
PTPRC
Gene source
Human
NCBI number
P08575
Recombinant
Yes
Source
HEK 293 cells
Purification
≥ 98%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
< 5 EU/mg
Tested activity
N/A
Biological activity
N/A
Reesults
N/A
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 0.2μm-filtered solution in PBS.
How to reconstitute
Reconstitute in 1X PBS to the desired protein concentration.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants